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Activity of lysosomal exoglycosidases in human gliomas

AbstractThere is a lot of data suggesting that modifications of cell glycoconjugates may be important in progression of cancer. In the present work we studied activities of lysosomal exoglycosidases:...

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Involvement of central β 2 -adrenergic, NMDA and thromboxane A 2 receptors in...

AbstractIntravenous (i.v.) injection of the endocannabinoid anandamide induces triphasic cardiovascular responses, including a pressor effect mediated via unknown central and peripheral mechanism(s)....

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Siglec-8 in Induced Sputum of COPD Patients

AbstractChronic obstructive pulmonary disease (COPD) is related to infiltration and activation of inflammatory cells in airways and pulmonary tissue. In COPD, neutrophils are prominent, while...

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Altered Histone Deacetylase Activity and iNOS Expression in Cells Isolated...

AbstractChronic obstructive pulmonary disease (COPD) is the only major disease with increasing death rate. In COPD, progressive reduction in quality of life is closely related to the increasing...

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Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells...

AbstractThe aim of this work was to assess the role of ethanol-derived acetate and acetate-mediated histone acetylation in arachidonic acid-induced stress in HepG2 cells and cells overexpressing...

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Inhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of...

AbstractRecent studies show that several Siglec receptors, such as Siglec-8 and Siglec-14, may be important therapeutic targets in asthma and COPD. Siglecs are a family of lectins belonging to the...

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Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with...

AbstractImmune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) may be involved in the regulation of chronic inflammation in chronic obstructive pulmonary disease (COPD)....

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Crosstalk Between Co-cultured A549 Cells and THP1 Cells Exposed to Cigarette...

AbstractCigarette smoke (CS) is considered as a major etiological factor in the pathogenesis of chronic obstructive pulmonary disease. In this study we used A549 cells and THP-1 cells grown for 24 h in...

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Intracellular and Extracellular Cytokines in A549 Cells and THP1 Cells...

AbstractCigarette smoke (CS) activates inflammatory cells and increases cytokine levels producing local and systemic inflammation. To assess changes in intracellular and extracellular cytokine levels...

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MicroRNA-9 and Cell Proliferation in Lipopolysaccharide and...

AbstractIn this study we assessed microRNA-9 (miR-9) levels (RT-PCR) and cell proliferation (flow cytometry) in naïve and desialylated human alveolar epithelial cells (A549 cells), grown for 24 h in...

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